Understanding the female libido system

Viagra For Women: Understanding The Female Libido System

As cisgender women and other AFAB (assigned female at birth) individuals approach middle age and beyond, it's not uncommon for them to experience decreased libido (innate sexual desire or drive). As a result, many women are turning to Viagra to address their diminished sexual desire. 

But what exactly is Viagra, and how does it work in the context of women's sexual health? This article will answer these questions and more! We'll explore the following topics to help you better understand this subject: 

  • What is Viagra? 
  • Benefits of using Viagra for women 
  • Types of Viagras for women 
  • Causes of low libido for women 
  • Things to consider in choosing Viagra for women 

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What Is Viagra? 

Viagra (generic name, sildenafil citrate) is a medication commonly prescribed to treat erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation.1 This helps men achieve and maintain an erection sufficient for sexual activity. 

The US Food and Drug Administration (FDA) approved Viagra in 1998. Since then, two other drugs have been approved to treat low libido in women. People call these drugs "Viagra for females."


How Does Viagra Work For Women? 

While Viagra was initially developed to treat erectile dysfunction in men, its effectiveness in women has been a topic of research and discussion. 

The active ingredient in Viagra, sildenafil, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which helps increase blood flow to the genital area. This increased blood flow can potentially have a positive effect on sexual function in women as well. 

One research in 2014 found that Viagra may help increase blood flow and sensitivity in the female genital area.2 

However, it is important to note that the FDA has not approved Viagra for use in women, specifically for treating low libido or sexual dysfunction. 

Research on its effectiveness and safety in women is still limited, and further studies are needed to understand its potential benefits and risks fully.


Benefits Of Using Viagra For Women 

When it comes to women, the benefits of using Viagra are still being explored and researched. However, some research has suggested the following benefits: 


Increased Sexual Arousal 

Viagra may potentially enhance sexual arousal in women by increasing blood flow to the genital area, which could lead to heightened sensitivity and improved sexual satisfaction. 

It may also help with vaginal lubrication, as increased blood flow can promote natural lubrication during sexual activity.2 This can contribute to a more comfortable and pleasurable sexual experience for women.


Psychological Benefits 

For women who experience distress or frustration due to sexual difficulties, the potential benefits of Viagra could extend beyond the physical realm. Improved sexual function and satisfaction could positively impact overall well-being and self-esteem, leading to increased confidence in intimate relationships.


Increased confidence


Treatment For Sexual Dysfunction 

Some studies have explored Viagra as a potential treatment for female sexual dysfunction, including conditions like female sexual interest and arousal disorder (FSIAD), if it stems from the use of antidepressants.3 

It is crucial to note that the use of Viagra in women is considered off-label, meaning the FDA does not officially approve it for this purpose. As such, it is recommended to consult with a healthcare professional to discuss potential risks, benefits, and alternative treatment options before considering the use of Viagra.


Types Of Viagras For Women 

In 2015 and 2019, the US Food and Drug Administration (FDA) approved two drugs for the treatment of FSIAD: Addyi (flibanserin) and Vyleesi (bremelanotide), respectively.4 

Let's discuss these two drugs in more detail.


Bremelanotide 

Bremelanotide, commonly known by the brand name Vyleesi, is one of the drugs approved by the US Food and Drug Administration (FDA) in 2019 for treating low libido in women. 

It belongs to a class of medications known as melanocortin receptor agonists. Bremelanotide works by activating certain receptors in the brain, specifically the melanocortin receptors, which play a role in sexual arousal and desire. 

Unlike Addyi, which is taken orally, Vyleesi is administered through a self-injection into the abdomen or thigh at least 45 minutes before anticipated sexual activity. This method of administration allows for a more rapid onset of action compared to oral medications. 

It is important to note that Vyleesi is not intended for daily use but rather on an as-needed basis, as determined by a healthcare professional.


Flibanserin 

Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause. 

It was approved by the US Food and Drug Administration (FDA) in 2015 as the first medication for treating low libido in women. 

Flibanserin targets neurotransmitters in the brain, specifically serotonin and dopamine, to help increase sexual desire. It increases dopamine and norepinephrine (both responsible for sexual excitement) and decreases serotonin, which is responsible for sexual inhibition. 

Addyi is taken orally, typically once daily at bedtime. However, it is important to note that this treatment is not a quick-fix solution and may take several weeks of regular use to see noticeable improvements in sexual desire. It is also meant for long-term use and should be taken consistently as prescribed by a healthcare professional.


Natural Viagra For Women 

In addition to the FDA-approved medications, there are also natural alternatives or supplements often referred to as "natural Viagra" for women. These natural alternatives include herbs, vitamins, minerals, and other plant extracts that have been proven beneficial for female sexual health. 

Let's explore some of these natural options:


Tribulus Terrestris 

Tribulus Terrestris is a natural herb that has been used traditionally in Ayurvedic medicine as a tonic and aphrodisiac and in European folk medicine to increase sexual potency. 

Several studies have found that it can help improve sexual desire and enhance libido in women.5


Ginkgo 

Also known as Ginkgo biloba, this powerful herb has been used in traditional Chinese medicine for centuries to enhance overall sexual function. Ginkgo is believed to increase blood flow to the genital area, improving women's arousal and sensitivity. 

In one open trial, ginkgo extracts were found to be 84% effective in reducing sexual dysfunction caused by antidepressant SSRIs.6


Ginseng 

Panax ginseng comes from the root of the plant in the genus Panax. It has been used in traditional Chinese medicine for centuries to enhance sexual function largely by opening (dilating) the arteries. This increases blood flow into the genitals, which improves lubrication and clitoral sensitivity in women. 

Studies have suggested that ginseng may significantly improve hot flashes, menopausal symptoms, and quality of life in menopausal women.7


Maca 

Maca is a nutrient-rich superfood packed with vitamins, minerals, and antioxidants. It originated in the Peruvian Andes mountains and has been used for thousands of years as food and as a natural remedy for various health conditions, including low sex drive and infertility. 

In a 2015 study, maca root was found to be an effective treatment for antidepressant-induced sexual dysfunction in women.8


Saffron 

Saffron, a spice derived from the Crocus sativus flower, has long been prized for its distinct flavor and aroma. However, it's also a natural aphrodisiac that has been used for centuries to improve sexual desire and arousal in both men and women. Saffron contains crocin (an active compound) that enhances mood and stimulates sexual desire. 

In a 2012 study, saffron supplementation was found to improve fluoxetine-induced sexual problems, including arousal, lubrication, and pain in women.9 

This study suggests that saffron may be a promising natural option for enhancing sexual health in women.


CBD 

Cannabidiol (CBD) is a non-intoxicating compound derived from the cannabis plant. While there isn't sufficient scientific evidence specifically on CBD's direct effects on female sexual health, some anecdotal reports and preliminary research suggest that it may have potential benefits. 

CBD is known for its relaxation and anti-anxiety properties,10 which could indirectly contribute to reducing stress and enhancing the overall sexual experience. It's also a vasodilator, which means it can help improve blood flow to the genital area, leading to increased arousal and sensitivity. 

Additionally, CBD has been shown to interact with the endocannabinoid system, which regulates various physiological processes, including sexual function. The endocannabinoid system is involved in the release of neurotransmitters, such as dopamine, which is known to be associated with pleasure and reward.11 By modulating the endocannabinoid system, CBD may indirectly affect dopamine levels, potentially enhancing sexual pleasure and satisfaction in women. 

When combined, all these factors contribute to the potential effectiveness of CBD as a natural alternative or supplement for female sexual health. However, it is important to note that more research is needed to fully understand the specific effects of CBD on female sexual function and to determine the optimal dosage and administration methods. 

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What Is Female Libido? 

Also known as sex drive, female libido refers to a woman's overall desire for sexual activity. It is influenced by various factors, including hormonal changes and psychological factors. 

Hormones such as estrogen and progesterone play a crucial role in regulating a woman's sexual desire and arousal. 

Estrogen, primarily produced by the ovaries, helps maintain vaginal lubrication, enhances blood flow to the genitals, and contributes to overall sexual satisfaction. 

Progesterone, another hormone produced by the ovaries, helps balance estrogen levels and can affect mood and energy levels, both of which can impact libido. 

A healthy libido is essential for a satisfying sex life and can be a sign of overall wellness.


How Does Female Libido Work? 

Female libido is a complex interplay of physical and psychological factors. At a physiological level, the brain plays a central role in regulating sexual desire. The hypothalamus, a region in the brain, releases hormones that stimulate the production of estrogen and progesterone. These hormones, in turn, affect the reproductive organs and the rest of the body. 

When a woman feels sexually aroused or experiences sexual stimuli, the brain sends signals to the genital area, triggering a series of physiological responses. Blood flow to the pelvic region increases, leading to engorgement of the clitoris and vaginal walls. The body also produces natural lubrication to facilitate sexual intercourse. 

It's important to note that female libido is highly variable and can fluctuate throughout a woman's life. Factors like menstrual cycle, pregnancy, menopause, and aging can all affect sexual desire.


Causes Of Low Libido For Women 

Low libido in women can be caused by a variety of factors, including physical, psychological, and lifestyle factors. 

Physical causes can include medical conditions such as diabetes, hormonal imbalances, or menopause. 

Psychological causes can range from stress and depression to anxiety and relationship issues. 

Lifestyle factors like lack of exercise, poor diet, alcohol use, or smoking can also contribute to low libido. 

Additionally, some medications can interfere with sexual desire, such as those used to treat depression or high blood pressure. 

It is important to speak with a healthcare professional to determine the cause of low libido in order to receive the appropriate treatment.


How To Improve Female Libido? 

There are various ways to improve female libido and enhance overall sexual desire. Here are some strategies that can help: 


Hormone Replacement Therapy (HRT) 

HRT involves using medications that contain hormones like estrogen and progesterone to supplement or replace the body's natural hormone levels. By restoring hormonal balance, HRT can help alleviate symptoms of low libido caused by hormonal fluctuations, particularly during menopause or other hormonal imbalances.


Psychotherapy 

Psychotherapy, also known as talk therapy or counseling, can benefit women experiencing low libido due to psychological factors. A trained therapist can help address underlying issues such as stress, anxiety, relationship problems, body image concerns, or past traumas that may be affecting sexual desire. 

Through therapy, women can gain insight, develop coping strategies, and improve communication with their partners, leading to increased sexual satisfaction and a healthier libido.


CBD Products 

Taking high-quality CBD products from a reputable source like FOCL can also help improve female libido. However, it's important to consult with a healthcare professional before starting any new supplement to ensure it is safe and appropriate for individual use.


CBD products


Things To Consider In Choosing Viagra For Women 

When it comes to choosing the right Viagra for women, there are a few things to consider: 

  1. Individual Needs And Preferences 

Different formulations may have varying mechanisms of action, and their suitability can depend on factors such as the type of sexual dysfunction you are experiencing, your overall health, and personal preferences. Discuss your concerns and goals with a healthcare professional who can offer tailored recommendations based on your specific situation. 

  1. Quality And Legitimacy

Ensure the product you choose is from a reputable source. Check for valid certifications and licenses, as well as positive customer reviews and testimonials. 

  1. Effectiveness And Safety Profile

Consider the effectiveness and safety profile of the product you are considering. Look for clinical studies and research that support its efficacy in treating female sexual dysfunction. 

Additionally, check for any warnings or precautions associated with its use, particularly if you have any pre-existing medical conditions or are taking other medications. 

A reliable and reputable product should have undergone rigorous testing and received approval from relevant regulatory authorities.


When To See A Doctor? 

If you are experiencing persistent or distressing low libido, it is advisable to schedule an appointment with a healthcare professional. A doctor or a specialist in sexual health can help determine the underlying cause of your low libido and recommend appropriate treatment options. 

Additionally, it is essential to seek medical attention if you are experiencing other symptoms alongside low libido. This may include additional symptoms such as pain during intercourse, vaginal dryness, or significant changes in your menstrual cycle. 

Seeking medical advice is also crucial if you have concerns about your overall sexual health and well-being. Remember, a healthcare professional can provide personalized guidance and support tailored to your specific needs.


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    FAQs 

    Is it safe for females to take Viagra? 

    While some studies have explored the potential use of Viagra for women, its effects, safety, and appropriate dosage for women are still being investigated. The FDA (Food and Drug Administration) has also not approved Viagra for use by women. 

    Therefore, women should consult their healthcare provider before considering Viagra as a treatment option. 


    Is Viagra for women safe for the liver? 

    Research is still ongoing regarding the safety of Viagra for women and its potential impact on liver health. However, there have been at least five reports of acute liver injury attributed to sildenafil use, but no instances of acute hepatic failure.12 


    Should Viagra for women be taken every day? 

    The dosage and frequency of Viagra should be determined by a doctor and should be taken as prescribed. Taking too much Viagra can lead to serious health complications, so it is important to follow the doctor's instructions. If you’re taking any of the alternatives listed above, work with your doctor to determine what a safe dosage is and how to use it. If you’re using a natural solution, work with a healthcare professional to learn more about whether or not that supplement is a good fit for you. If you experience any side effects, report them to your doctor immediately.


    How much Viagra should a woman take? 

    The amount of Viagra (or similar alternative) a woman should take will depend on her individual health condition and the advice of her doctor. They will provide you with a treatment plan that addresses your specific needs. Don’t deviate from this treatment plan or incorporate something new into it unless advised by your doctor. 


    Can I buy Viagra for women over the counter? 

    No, prescription medications like Viagra for women are not available over the counter. It is a prescription medication and can only be obtained with a doctor's prescription.

     

    Sources: 

    1. Huang, S. A., & Lie, J. D. (2013, July). Phosphodiesterase-5 (PDE5) inhibitors in the management of erectile dysfunction. P & T : a peer-reviewed journal for formulary management. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776492/ 
    2. Lo Monte, G., Graziano, A., Piva, I., & Marci, R. (2014, November 7). Women taking the “blue pill” (sildenafil citrate): Such a big deal? Drug design, development and therapy. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232035/ 
    3. Thomas, H. N., & Thurston, R. C. (2016, May). A biopsychosocial approach to women's sexual function and dysfunction at midlife: A narrative review. Maturitas. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808247/ 
    4. L;, M. B. L. (n.d.). Bremelanotide and flibanserin for low sexual desire in women: The fallacy of regulatory precedent. Drug and therapeutics bulletin. https://pubmed.ncbi.nlm.nih.gov/34642243/#:~:text=The%20US%20Food%20and%20Drug,bremelanotide%20(Vyleesi)%20in%202019. 
    5. S;, de S. K. F. (n.d.). Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: A randomized, double-blinded, placebo-controlled trial. Menopause (New York, N.Y.). https://pubmed.ncbi.nlm.nih.gov/27760089/ 
    6. B;, C. A. (n.d.). Ginkgo biloba for antidepressant-induced sexual dysfunction. Journal of sex & marital therapy. https://pubmed.ncbi.nlm.nih.gov/9611693/ 
    7. Author links open overlay panelHye Won Lee a, a, b, herbs, H. individual, & AbstractPurposeThis systematic review aimed to update the evidence of ginseng on menopausal women's health care.MethodsWe searched six databases (PubMed. (2022, June 3). Using ginseng for menopausal women's Health Care: A systematic review of randomized placebo-controlled trials. Complementary Therapies in Clinical Practice. https://www.sciencedirect.com/science/article/pii/S1744388122000834#: 
    8. Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S. W., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411442/ 
    9. Saffron for treatment of fluoxetine‐induced ... - wiley online library. (n.d.-d). https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2282 
    10. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015a, October). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/ 
    11. Oleson, E. B., & Cheer, J. F. (2012, August 1). A brain on cannabinoids: The role of dopamine release in reward seeking. Cold Spring Harbor perspectives in medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405830/#:~:text=Importantly%2C%20also%2C%20the%20cannabinoid%2D,tonic%20and%20phasic%20dopamine%20release. 
    12. National Center for Biotechnology Information. (n.d.-c). https://www.ncbi.nlm.nih.gov/books/NBK548510/