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Can You Take CBD and Melatonin Together? Exploring the Pros and Cons

CBD and melatonin are two of the most popular prescription-free sleep aids on the market. It’s not always easy to decide which one is right for you. “Why not both?” you may be asking yourself. Can you take CBD with melatonin for extra sleep-promoting power? What are the benefits and risks of combining these two remedies?

Current evidence suggests that mixing CBD and melatonin can be a safe and effective way to maintain healthy sleep cycles. It can help you fall asleep and stay asleep despite obstacles like anxiety, jet lag, and annoying aches and pains. This combo may not be right for everyone, though. This article will give you an in-depth look at how cannabidiol and melatonin interact and what you should consider before taking them together.

We’ll also discuss how to find high-quality sleep products combining CBD with melatonin. The best version (if we do say so ourselves) is ours. FOCL Deep Sleep Gummies include an ideal ratio of melatonin and cannabinoids to fight sleep deprivation, and they’re manufactured according to exacting standards that keep them totally free from contaminants. They’re also vegan-friendly, naturally flavored, and covered by our money-back satisfaction guarantee.

Scroll on to learn what CBD and melatonin can do for your sleep health.

How Do CBD and Melatonin Affect Your Sleep Health?

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We have a detailed article on the differences between CBD and melatonin, but here are the key points to remember:

Melatonin For Sleep: The Basics

Melatonin is a sleep hormone that the body naturally produces inside the brain’s pineal gland. Among other functions, it helps to regulate your sleep-wake cycle. Melatonin production decreases when lots of light is hitting your eyes, then increases again as it gets dark, triggering feelings of drowsiness.

This cycle can be thrown off by irregular sleep schedules, making it harder to get to sleep on time. That’s why melatonin supplements are excellent for those trying to resume normal sleep patterns after disruptions like jet lag or late shifts at work.

Even if you’re not trying to make up for lost sleep, melatonin may help you start snoozing faster. Ingesting it at the right time is crucial — a daytime dose will likely throw your sleep cycle even further out of whack.

CBD For Sleep: The Basics

Unlike melatonin, CBD isn’t a naturally occurring hormone in humans — it’s found only in the cannabis plant. However, it allows the body to build up higher levels of a natural signaling molecule called anandamide. This neurotransmitter has many functions, but they include:

  • Relieving anxiety
  • Decreasing pain perception
  • Protecting against stress
  • Promoting deep, restful sleep

Using CBD for sleep can make it easier to forget your worries, aches, and pains, easing you into natural slumber.

Is It Safe to Take Melatonin and CBD Together?

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We spoiled this answer a little bit in the intro, but yes, CBD and melatonin can be taken together in reasonable doses. Many of the best CBD gummies for sleep include melatonin to enhance their effects.

A 2023 study tested various combinations of cannabinoids and melatonin on nearly 1,800 participants from around the United States. They found that only a small percentage of people experienced side effects, none of which were severe.

This answer may change as more research is published, but scientists don’t currently have any particular reason to think that these popular supplements are unsafe in combination. Pairing CBD with other medications can sometimes be risky because it may reduce the speed at which the liver breaks them down, but melatonin is considered to pose a minimal risk of liver damage. It may even help protect against some types of liver disease.

Can you take CBD gummies and melatonin safely?

CBD sleep gummies with melatonin should be a safe combination. The only difference when using edible cannabidiol is that the effects tend to be slower and milder but longer-lasting. Taking melatonin with a CBD gummy is often a great way to stay relaxed throughout the night.

Can you take CBD oil with melatonin safely?

Another popular way to consume CBD is in the form of oil-based tinctures. These can be dropped under the tongue for fast absorption so that you feel the effects more quickly. Using a melatonin-infused CBD sleep oil should be just as safe as taking melatonin with a CBD gummy.

What’s the best way to take CBD and melatonin together?

We’re confident that our Deep Sleep Gummies will provide the best experience for most users. They contain a carefully crafted blend of melatonin, CBD, CBN, and a small dose of THC to help you rapidly reach a deep, refreshing slumber.

Our sleep gummies are manufactured according to rigorous standards and tested by third-party labs to ensure they’re accurately dosed and free from harmful impurities. You can view the Certificates of Analysis on our website to verify that you’re getting exactly what it says on the label.

More than 85% of participants in an independent study said that FOCL Deep Sleep Gummies were the best product they’d ever tried for sleep support. If you don’t agree, you’ll get back what you spent thanks to our 60-day satisfaction guarantee.

Possible Downsides of CBD With Melatonin: Side Effects and Cost

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Although combining melatonin and CBD should be safe for most people, there are two potential drawbacks to consider:

  1. It may be more expensive. Products including multiple active ingredients naturally tend to cost more. If you get a good night’s sleep from CBD gummies without melatonin, the added potency you get from combining them may not be worth the price.
  2. There’s a greater risk of certain side effects. CBD and melatonin have some side effects in common. The most frequently reported one is grogginess the following day. Some people also feel dizziness or nausea. These effects tend to be fairly rare and mild, but you may be more likely to encounter them if you take CBD mixed with melatonin.

You can often minimize both of these disadvantages by knowing where to shop. Lower-quality products are more likely to have unpredictable amounts of CBD and melatonin, while some boutique sellers may be charging more for the packaging than the ingredients. Our buyer’s guide to CBD sleep gummies has some pointers on finding trustworthy sources.

Advantages of Taking CBD With Melatonin

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As we’ve seen, the evidence suggests it’s safe to pair melatonin with CBD gummies or oil. This can provide several potential benefits:

Faster Sleep

A fusion of CBD and melatonin may put you to sleep more rapidly than either ingredient by itself. Since they promote slumber in different ways, they can combine for a one-two “knockout punch” effect that many people say is remarkably effective at helping them drift off.

Improved Rest

Both melatonin and cannabidiol have shown positive effects on overall sleep quality in clinical trials. People taking these sleep aids often wake up less during the night and feel more refreshed the next day. In at least one clinical trial, people who received a combined dose of melatonin and CBD reported feeling better rested than those getting either substance on its own.

Tackling Multiple Sleep Disorders At Once

Some sleep problems may be better suited to one substance or the other. For example, you might be better off taking melatonin for circadian rhythm disorders and CBD gummies for anxiety-related insomnia.

But many people struggle to stay well-rested for more than one reason. Let’s say you’re stressed out due to overwork — you may be dealing with both a messed-up sleep cycle and a head full of racing thoughts that won’t let you fall asleep. When you mix CBD and melatonin, you can kill two birds with one dose.

Better Brain Health

The wellness benefits of these two molecules may go beyond the immediate perks of a good night’s sleep. Researchers have found evidence that both CBD and melatonin supplements may help protect brain cells against damage and degeneration. These results will need to be confirmed with further studies, but they suggest that melatonin and cannabidiol might work together to stave off dementia.

Using CBD and Melatonin Together: Frequently Asked Questions

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How much CBD and melatonin should you take for sleep?

The ideal dosages of these substances haven’t yet been firmly established. However, most sources agree that taking a fairly small amount of melatonin per night — between 0.3 and 5 mg — is generally best. The typical CBD dosage is higher, ranging anywhere from 5 to 100 mg.

Both of these can be affected by factors like body weight, metabolism, and individual tolerance. You’ll generally want to start with a small amount and work your way up until you find the dosage that helps you sleep best. We’d suggest beginning with ½-1 mg of melatonin and 12-25 mg of CBD.

How long does it take for CBD and melatonin to work?

The typical onset time for melatonin supplements is around 20-45 minutes. CBD may take slightly longer to kick in — around 30-60 minutes. Both substances tend to work faster when taken as tinctures under the tongue than in edible form.

How long do CBD and melatonin last?

The effects of CBD and melatonin can last for 2-8 hours. Edibles like CBD gummies tend to last longer than tinctures, though they don’t take effect as quickly.

What are the potential side effects of mixing CBD and melatonin?

As we mentioned above, the most likely side effect from this combo is daytime drowsiness, followed by nausea or vertigo. Other possible side effects include:

  • Dry mouth
  • Strange, vivid dreams
  • Diarrhea
  • Headaches
  • Loss of appetite

If you notice these unwanted effects, it may be helpful to scale back your dosage slightly. You may find that a smaller amount is enough to promote sleep without side effects.

What is the best time of day to take melatonin with CBD?

When using CBD and melatonin for sleep, you’ll almost always get the best effects from taking them in the mid-to-late evening. You should pop in a sleep gummy around an hour before you’re hoping to fall asleep.

When in doubt, it’s better to take melatonin and CBD too early than too late. A late dose is more likely to make you feel groggy the next day.

How often can you take CBD and melatonin together?

A single daily dose is your best bet for keeping your sleep patterns regular. Taking melatonin more than once a day will likely confuse your internal clock.

Try Melatonin and CBD Gummies For Superior Sleep Support

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If you’re ready to try melatonin and CBD for sleep, FOCL Deep Sleep Gummies are the way to go. Made with pure ingredients, natural flavors, and an uncompromising commitment to quality, they’ll help you drift off gently and wake up recharged. Order online to begin your 60-night risk-free trial!